Molecular Medicine publishes original research articles and expert commentaries on emerging concepts in the interdisciplinary field of molecular medicine. Considered the vanguard of the new millennium in which science truly complements the art of medicine, Molecular Medicine strives to understand the molecules key to normal body functioning and the pathogenesis of disease, and based on that knowledge, to design specific molecular tools for diagnosis, treatment and prevention. A nonprofit journal organized and peer-reviewed by expert scientists and editors, Molecular Medicine is committed to: • providing a venue where rigor and scholarship reign, • promoting and advancing scientific discourse, and<br /> • imparting a common language and understanding among diverse clinical groups, from allergists to virologists and everyone in between. Like the field, Molecular Medicine the journal continues to grow as it scales the heights of modern biomedical science. It has captured the imagination of many of the best basic science and clinical investigators. Pick up an issue today and see for yourself! http://www.molmed.org Science & Medicine 2008 Molecular Medicine Tue, 02 Jun 2009 09:52:09 -0400 mpuerta@NSHS.edu Tue, 02 Jun 2009 09:51:44 -0400 kstroud@optonline.net FeedForAll Mac v2.1 (2.1.0.2); http://www.FeedForAll.com/ http://www.molmed.org/images/MolMedCover_5_6_09.jpg http://www.molmed.org Insight into the Cellular and Molecular Basis of Disease 110 140 RA, Myocardial Infarction, and non-Hodgkin Lymphoma http://www.molmed.org/mp3s/Episode48.mp3 2466F574-4F7C-11DE-BD27-0014510BD93E-90521-0000104702057560-FFA Tue, 02 Jun 2009 09:50:11 -0400 Disease Awareness in May http://www.molmed.org/mp3s/Episode47.mp3 4AC46A44-4F7C-11DE-BD27-0014510BD93E-90521-0000104781E64ACE-FFA Tue, 02 Jun 2009 09:51:17 -0400 Bone marrow–derived endothelial progenitor cells (EPC) are critical for maintaining the integrity and health of the vasculature. In diabetes, however, the numbers of these cells in the circulation are reduced, which may lead to ischemic vascular disease in these patients. Loomans et al. demonstrate that hyperglycemia drives the fate of EPC away from forming helpful, proangiogenic cells <br /> capable of remodeling the endothelium to forming proinflammatory cells instead. Their work helps us appreciate the underlying cause of vascular complications in diabetes patients and may serve to outline a specific use of bone marrow cells in neovascularization therapy. http://www.molmed.org/content/2009/5_6_09/152_159.vanZonneveld.00032.PDF CD9B8AE6-A9BA-11DD-860A-0014510BD93E-733-0000002C57448DCD-FFA Mon, 27 Apr 2009 10:50:46 -0400 Congestive heart failure (CHF) can be the final result of a series of events including necrosis of the myocardium, coronary artery occulsion, and myocardial infarction (MI). Until recently it was thought that once cells in this tissue were damaged, there was no possibility for regeneration. Stavropoulou et al. examine the role of IGF expression in myocardium repair following MI in Wistar rats. The authors postulate that the IGF-1 isoforms, IGF-1Ea and MGF-E, each have unique roles to play in myocardial repair processes. This work could ultimately impact clinical options in the immediate aftermath of MI. http://www.molmed.org/content/2009/5_6_09/127_135.Koutsilieris.00012.pdf 6D4B89D4-916C-11DC-909A-0014510BD93E-17496-0000048FE4895858-FFA Mon, 27 Apr 2009 10:49:57 -0400 Vol 15/No 1-2 Published by The Feinstein Institute for Medical Research http://www.molmed.org/content/2009/5_6_09.htm F4FE4178-B947-11DC-AB6F-0014510BD93E-5990-0000015FEE23FAC9-FFA Mon, 27 Apr 2009 10:38:24 -0400 GTS-21 Attenuates Cytokine Production In Human Whole Blood And Human Monocytes TPC: Non-erythropoietic Tissue Protective Compound ... more     http://www.molmed.org E83EBF4E-8701-11DC-B50B-0014510BD93E-3049-0000012299B8F2DB-FFA Mon, 27 Apr 2009 10:52:39 -0400